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Lewy bodies comprise one of the most encountered nerve cell pathologies with an undefined biochemical composition (Spillantini et al., 1997). Aggregation of misfolded alpha-synuclein is a major contributor to the intraneuronal Lewy bodies (Coughlin et al., 2020). The accumulation of aggregated forms of alpha-synuclein in the cells of the brain causes synucleopathies, which are the […]
Dementia with Lewy body Read More »
Identifying the molecular basis of the characteristics that makes us human is by far one of the greatest challenges of biology and as humans, we have been searching for answers for our exceptionally developed brains for centuries. In between the millions of mutations and chromosomal rearrangements that have occured during our evolution lie the genetic
Human Accelerated Regions Read More »
Throughout the past decades, most of the research has been focused on 2D cultured cell lines. These rather classical cell lines are cheap, easy to handle, and amenable to numerous experimental techniques and methods [1,2]. However, their initial establishment is inefficient and involves extended genetic and phenotypic adaptation to culture conditions. As a result, cell
What Are Human Organoids, and Why Are They Important? Read More »
Plant genetic transformation is a significant technical development in modern science that has not only enabled basic insights into plant biology but has also heralded a new age in crop improvement and commercial farming. However, advancements in plant tissue culture technologies are required to streamline operational stages to enhance transformation efficiency. Furthermore, substantial emphasis must
Alcohol consumption is removed from the body by way of breathed air, as has been proven as early as the 19th century [1]. Since breath is a sample that is easier to obtain than blood, the determination of the alcohol concentration in breath has been studied since 1927 [2]. Different BrAC analysis techniques were developed
The Elimination Rates of Alcohol from Breath Read More »