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Biosensors are analytical devices that measure biological and chemical reactions by generating signals proportioned to the concentration of the analyte in the reaction. They consist of a bioreceptor that can detect a specific biological (or chemical) element and a transducer that converts the energy form through a process known as ‘signalisation’. Biosensors are commonly used […]
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Lewy bodies comprise one of the most encountered nerve cell pathologies with an undefined biochemical composition (Spillantini et al., 1997). Aggregation of misfolded alpha-synuclein is a major contributor to the intraneuronal Lewy bodies (Coughlin et al., 2020). The accumulation of aggregated forms of alpha-synuclein in the cells of the brain causes synucleopathies, which are the
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Identifying the molecular basis of the characteristics that makes us human is by far one of the greatest challenges of biology and as humans, we have been searching for answers for our exceptionally developed brains for centuries. In between the millions of mutations and chromosomal rearrangements that have occured during our evolution lie the genetic
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Throughout the past decades, most of the research has been focused on 2D cultured cell lines. These rather classical cell lines are cheap, easy to handle, and amenable to numerous experimental techniques and methods [1,2]. However, their initial establishment is inefficient and involves extended genetic and phenotypic adaptation to culture conditions. As a result, cell
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Plant genetic transformation is a significant technical development in modern science that has not only enabled basic insights into plant biology but has also heralded a new age in crop improvement and commercial farming. However, advancements in plant tissue culture technologies are required to streamline operational stages to enhance transformation efficiency. Furthermore, substantial emphasis must