A Rare Disease Review: Fatal Familial Insomnia (FFI)

What Is Fatal Familial Insomnia (FFI)? Fatal Familial Insomnia (FFI), a highly rare form of brain disease that falls under the umbrella of Transmissible Spongiform Encephalopathies (TSE), is characterized by neurodegenerative alterations brought on by the prion protein (PrP), an abnormally constitutively produced protein 1,2. It is characterized by an inability to fall asleep (insomnia), […]

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