2021-2022

Guillain-Barre Syndrome

GBS, also known as Guillain-Barré syndrome, is an extremely uncommon and possibly lethal autoimmune disorder that mainly affects people who were previously healthy and is characterized by progressive muscle weakness and demyelination of the peripheral nervous system1,2,3. Contrary to multiple sclerosis (MS), this disorder does not impact the central nervous system4. Epidemeiology Global Incidence The […]

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Agrobacterium tumefaciens-mediated Transformation

The genus Agrobacterium stands for saprophytic bacteria species and lives in the soil microflora1. Four of these Agrobacterium species cause neoplastic diseases in various plants. These are: “crown gall” caused by Agrobacterium tumefaciens, “hairy root” caused by Agrobacterium rhizogenes, and “cane gall” caused by A. rubi. The last one, which is called A. vitis and

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Kalıtsal Kolorektal Kanserler ve Tedavileri Nelerdir?

Kalın bağırsağın 150-180 cm’lik üst kısmı “kolon” ve 15-17 cm’lik alt kısmı ise “rektum” olarak adlandırılır. Kalın bağırsaktaki kolon ve rektum bölgelerinde görülen kansere ise kolorektal kanser (CRC) adı verilmektedir1,2,5. Kolorektal kanser, Batı yarımkürede en çok görülen üçüncü ve dünya çapında kanser ölümlerinin en yüksek olduğu dördüncü kanser türüdür ve insidansı yaşla doğru orantılı olarak

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RNA Interference And Clinical Applications

Considering the two most common types of diseases caused by mRNA activity, one of them is virus-related and the other is cancer-related1. These diseases cause viral or abnormal proteins to be encoded by mRNA1. For instance, some ORFs found in coronaviruses encode viral structural proteins2. After viral cells enter the body, they undergo RNA translation

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